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ProSys Technology specialise in the design, manufacture and validation of Aseptic Isolators and RABs Systems to meet the ever-changing requirements of the Pharmaceutical and Bio-Pharmaceutical industries.
As an industry leader in Containment Isolator Systems, ProSys Technology provides various single nanogram containment systems with integrated Rotovaps, for customers in the USA and Singapore. The Isolators are designed to integrate with the Rotary Evaporator, Tray Dryers, weigh scales and other process equipment.
We started with two Isolators , a Tray Dryer & Dispensing Isolator and a Rovotap Isolator. Both Isolators operate under turbulent flow and negative pressure HEPA filtered air, designed for a task-based Containment Performance Target (CPT) of 5nanogram/m3. The Isolators have an electrical area rating of Class 1 Division 2 Group C&D. While in construction, 316L Stainless Steel was installed, along with toughened glass viewing windows. Inlet and exit airlock chambers were included for uni-directional material flow. Allen Bradley PLC with 10″ PanelView Plus HMI controls the three operation modes of the Isolators: Nitrogen, room air and breach.
Within the Tray Dryer and Dispensing Isolator was a Tray Dryer connected to the rear wall. There were five glove ports in the main chamber and a 350mm RTP System on the exit airlock. The Rotovap Isolator was to integrate a 20 liter Buechi Rotary Evaporator, model R-220 EX in the main chamber. The main chamber included three levels of four gloves and a 350mm RTP system on the exit airlock.
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After thorough review, and multiple revisions later, of the process and integrated equipment with our customer, a single process Isolator with multiple chambers was settled on. The 350mm RTP was increased to a 460mm RTP to enable removal of the 20 liter round bottom flask. The Isolator was to be separated in to three sections for shipping and room access purposes. Photos of the finished Isolator can be seen above.
ProSys Technology approaches every project as our customer’s partner, to assist them in producing an Isolator System that it the best solution for their process and operators.
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